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The UNSC Ether-à-go-go is a vessel of the UNSC Office of Naval Intelligence.

Behind the ScenesEdit

It is named after ether-a-go-go, a murine gene that encodes a protein formally known as "potassium voltage-gated channel, subfamily H (eag-related), member 1" (KCNH1). In humans, the homologue is known as "potassium voltage-gated channel, subfamily H (eag-related), member 1" (KCNH2), and is otherwise known as human ether-a-go-go related gene (hERG). hERG is an important target for discovery toxicology in pharmaceutical development of lead and hit small-molecule chemical compounds for drug discovery because its blockade is a common non-specific side effect of many pharmacological agents, and its blockade induces prolongation of the QT cardiac arrhythmia and may induce fatal cardiac tachyarrythmia (Torsades de Pointe)[1].

ReferencesEdit

  1. Kramer et. al (2007). The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates. Nature Reviews Drug Discovery (6): 636-649.
UNSC Navy
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Corvettes UNSC Apache · UNSC Centaur · UNSC Deterrent · UNSC Flurry · UNSC Speed of Sound · UNSC Thunderstrike
Prowlers UNSC Bend Sinister · UNSC Calyx of Night · UNSC Clairvoyance · UNSC Ether-à-go-go · UNSC Lost a Fin · UNSC Shade
Stations ONI Deep Space Naval Observatory · UNSC Singapore Station · Spirit of Progress
Vessel Classifications Stealth Reconnaissance Frigate · Sojourn-class battle cruiser
Other UNSC Atlantis · UNSC BC-5821Z
Commands UNSC Second Fleet · UNSC Fourth Fleet
Formations CAM-327-17 Task Force · Task Force Gamma
Special BLUE CUBE · Operation: PURPLE WILLOW · RED SKY · WHITE SANDAL · RIVER HEDGE · MARBLE COURT
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